31618-90-3
- Product Name：Diethyl P-Toluene Sulfonyloxy Methyl Phosphonate(Desmp)
- MF：C12H19O6PS
- Purity：99%
- Molecular Weight：322.319
Product Details
Cost-effective and customizable Diethyl P-Toluene Sulfonyloxy Methyl Phosphonate(Desmp) 31618-90-3 in stock
- Molecular Formula:C12H19O6PS
- Molecular Weight:322.319
- Appearance/Colour:Pale yellow oil
- Vapor Pressure:1.39E-07mmHg at 25°C
- Refractive Index:1.498
- Boiling Point:441.7 °C at 760 mmHg
- Flash Point:220.9 °C
- PSA：97.09000
- Density:1.255 g/cm3
- LogP:4.00470
Diethyl (tosyloxy)methylphosphonate(Cas 31618-90-3) Usage
InChI:InChI=1/C12H19O6PS/c1-4-16-19(13,17-5-2)10-18-20(14,15)12-8-6-11(3)7-9-12/h6-9H,4-5,10H2,1-3H3
31618-90-3 Relevant articles
Monosubstituted pillar[5]arene functionalized with (amino)phosphonate fragments are "smart" building blocks for constructing nanosized structures with some s-and p-metal cations in the organic phase
Nazarova, Anastasia A.,Yakimova, Luidmila S.,Padnya, Pavel L.,Evtugyn, Vladimir G.,Osin, Yuri N.,Cragg, Peter J.,Stoikov, Ivan I.
, p. 14450 - 14458 (2019)
Monosubstituted pillar[5]arenes containi...
Preparation method of diethyl p-toluenesulfonyloxymethylphosphonate
-
Paragraph 0092-0094; 0097-0106; 0110-0115; 0119-0125, (2021/07/17)
The invention relates to a preparation m...
Development and optimization of halogenated vinyl sulfones as Nrf2 activators for the treatment of Parkinson's disease
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supporting information, (2021/01/06)
The Kelch-like ECH-associated protein 1 ...
NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF
-
Paragraph 0060-0061, (2021/06/25)
The present invention relates to a novel...
Asymmetric Synthesis of Chiral 1,3-Disubstituted Allylsilanes via Copper(I)-Catalyzed 1,4-Conjugate Silylation of α,β-Unsaturated Sulfones and Subsequent Julia-Kocienski Olefination
Jia, Xue-Shun,Wang, Xian-Liang,Xiao, Jun-Zhao,Yin, Liang,Yin, Xing-Hao
, p. 1916 - 1922 (2021/06/07)
A general synthesis of chiral 1,3-disubs...
31618-90-3 Process route
-
-
50-00-0,30525-89-4,61233-19-0
formaldehyd
-
-
762-04-9
phosphonic acid diethyl ester
-
-
98-59-9
p-toluenesulfonyl chloride
-
-
31618-90-3
diethyl (p-toluenesulfonyloxymethane)phosphonate
| Conditions | Yield |
|---|---|
|
formaldehyd; phosphonic acid diethyl ester;
With
triethylamine;
In
toluene;
at 85 - 90 ℃;
for 3h;
Heating / reflux;
p-toluenesulfonyl chloride;
With
triethylamine;
at 4 - 20 ℃;
for 14.75h;
|
77.6% |
|
formaldehyd; phosphonic acid diethyl ester;
With
triethylamine;
In
toluene;
at 90 - 125 ℃;
for 5h;
Inert atmosphere;
p-toluenesulfonyl chloride;
With
triethylamine;
In
toluene;
at 0 - 20 ℃;
|
47% |
|
formaldehyd; phosphonic acid diethyl ester;
With
triethylamine;
In
toluene;
at 70 ℃;
Inert atmosphere;
Reflux;
p-toluenesulfonyl chloride;
With
triethylamine;
In
toluene;
at 5 - 20 ℃;
Inert atmosphere;
|
|
|
formaldehyd; phosphonic acid diethyl ester;
With
triethylamine;
In
toluene;
at 87 ℃;
for 2h;
p-toluenesulfonyl chloride;
In
toluene;
|
|
|
formaldehyd; phosphonic acid diethyl ester;
With
triethylamine;
In
toluene;
at 87 ℃;
for 3h;
Inert atmosphere;
Reflux;
p-toluenesulfonyl chloride;
With
triethylamine;
In
toluene;
at -2 - 22 ℃;
Inert atmosphere;
|
-
-
3084-40-0
diethyl (1-hydroxymethyl)phosphonate
-
-
31618-90-3
diethyl (p-toluenesulfonyloxymethane)phosphonate
| Conditions | Yield |
|---|---|
|
With
triethylamine;
In
diethyl ether;
at -10 - 20 ℃;
for 17h;
|
75% |
31618-90-3 Upstream products
-
3084-40-0
diethyl (1-hydroxymethyl)phosphonate
-
98-59-9
p-toluenesulfonyl chloride
-
7016-78-6
(diethoxyphosphoryl)methyl acetate
-
50-00-0
formaldehyd
31618-90-3 Downstream products
-
143056-54-6
diethyl <<4-(hydroxymethyl)phenoxy>methyl>phosphonate
-
129174-12-5
5'-O-
-
129151-56-0
5'-O-<(diethylphosphono)methyl>-2',3'-dideoxycytidine
-
129151-62-8
N3-<(diethylphosphono)methyl>-5'-O-benzoyl-3'-deoxy-3'-fluorothymidine
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